For a double strand DNA, one strand is given below: The amount of...

For a double strand DNA, one strand is given below: The amount of energy required to split the double strand DNA into two single strands is _______ kcal $\mathrm{mol}^{-1}$. [Given: Average energy per $\mathrm{H}$-bond for A-T base pair $=1.0 \mathrm{kcal} \mathrm{mol}^{-1}, \mathrm{G}-\mathrm{C}$ base pair $=1.5 \mathrm{kcal}$ $\mathrm{mol}^{-1}$, and A-U base pair $=1.25 \mathrm{kcal} \mathrm{mol}^{-1}$. Ignore electrostatic repulsion between the phosphate groups.]