NEET 2026
- Exam
- NEET
- Year
- 2026
- Subject
- Biology
- Chapter
- Chapter
NEET 2026 · Biology · Chapter
Which of the following hormones acts principally on hepatocytes to...
Which of the following hormones acts principally on hepatocytes to stimulate both glycogenolysis and gluconeogenesis, thereby leading to hyperglycemia?
Options
- AMelatonin
- BGlucagon
- CCalcitonin
- DInsulin
Correct answer
B. Glucagon
Step-by-step solution
Glucagon is a peptide hormone secreted by the alpha cells of the islets of Langerhans in the pancreas.
It acts principally on the liver cells (hepatocytes) and stimulates glycogenolysis (the breakdown of glycogen into glucose) and gluconeogenesis (the synthesis of glucose from non-carbohydrate precursors).
These processes increase the concentration of glucose in the blood, leading to hyperglycemia.
Insulin has the antagonistic effect, promoting glycogenesis and leading to hypoglycemia. Melatonin regulates the diurnal rhythm of the body, and calcitonin regulates blood calcium levels.
Answer: Glucagon
It acts principally on the liver cells (hepatocytes) and stimulates glycogenolysis (the breakdown of glycogen into glucose) and gluconeogenesis (the synthesis of glucose from non-carbohydrate precursors).
These processes increase the concentration of glucose in the blood, leading to hyperglycemia.
Insulin has the antagonistic effect, promoting glycogenesis and leading to hypoglycemia. Melatonin regulates the diurnal rhythm of the body, and calcitonin regulates blood calcium levels.
Answer: Glucagon