NEET 2026
- Exam
- NEET
- Year
- 2026
- Subject
- Chemistry
- Chapter
- Chapter
NEET 2026 · Chemistry · Chapter
What is the correct decreasing order of reactivity of the following...
What is the correct decreasing order of reactivity of the following alkyl halides towards sodium methoxide in a Williamson synthesis?
I.
II.
III.
IV.
I.
II.
III.
IV.
Options
- AI II IV III
- BIII II IV I
- CIII IV II I
- DIV III II I
Correct answer
C. III IV II I
Step-by-step solution
Williamson ether synthesis proceeds via an mechanism.
The rate of an reaction is inversely proportional to the steric hindrance around the electrophilic carbon and is enhanced by the stabilization of the transition state.
Compound III () is a benzylic halide. Its transition state is highly stabilized by the adjacent phenyl ring through conjugation, making it the most reactive.
Compound IV () is an unbranched primary alkyl halide with minimal steric hindrance.
Compound II () is a primary alkyl halide but has a methyl group at the -position. This branching increases steric hindrance, making it less reactive than IV.
Compound I () is a secondary alkyl halide, which is more sterically hindered at the -carbon than primary alkyl halides, making it the least reactive.
Therefore, the decreasing order of reactivity is III IV II I.
Answer: III IV II I
The rate of an reaction is inversely proportional to the steric hindrance around the electrophilic carbon and is enhanced by the stabilization of the transition state.
Compound III () is a benzylic halide. Its transition state is highly stabilized by the adjacent phenyl ring through conjugation, making it the most reactive.
Compound IV () is an unbranched primary alkyl halide with minimal steric hindrance.
Compound II () is a primary alkyl halide but has a methyl group at the -position. This branching increases steric hindrance, making it less reactive than IV.
Compound I () is a secondary alkyl halide, which is more sterically hindered at the -carbon than primary alkyl halides, making it the least reactive.
Therefore, the decreasing order of reactivity is III IV II I.
Answer: III IV II I