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The secondary structures of proteins, such as the -helix and -pleated sheet, arise due to the regular folding of the polypeptide chain. This folding is primarily stabilized by hydrogen bonding between which of the following specific groups?

Options

  1. ATerminal - NH ₂ and - COOH groups of the polypeptide chain
  2. BSide chain ( -R ) groups of the constituent amino acids
  3. C- OH and - C=O groups present in the amino acid residues
  4. D- C=O and - NH - groups of the peptide bonds

Correct answer

D. - C=O and - NH - groups of the peptide bonds

Step-by-step solution

The secondary structure of a protein refers to the shape in which a long polypeptide chain exists, such as -helix and -pleated sheet. These structures arise due to the regular folding of the backbone of the polypeptide chain. This folding is stabilized by hydrogen bonding between the carbonyl oxygen ( - C=O ) of one peptide bond and the amide hydrogen ( - NH - ) of another peptide bond along the backbone. Interactions between side chain ( -R ) groups are primarily responsible for the tertiary structure, while termi

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