Given below are two statements: one is labelled as Assertion A and the other is labelled as Reason R. Assertion A: Denaturation of a protein results in the loss of its biological activity and uncoiling of its -helix structure. Reason R: Denaturation involves the cleavage of peptide bonds, which alters the primary sequence of the protein. In the light of the above statements, choose the most appropriate answer from th

Step-by-step solution

Denaturation of proteins leads to the disruption of secondary and tertiary structures. The uncoiling of the -helix (which is a secondary structure) occurs, and the protein loses its specific three-dimensional shape, resulting in the loss of its biological activity. Thus, Assertion A is correct. During denaturation, the primary structure of the protein remains completely intact. The strong covalent peptide bonds linking the amino acids are not cleaved, meaning the primary sequence is unaltered. Thus, Reason R is inc