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Which of the following statements regarding the structure of proteins is incorrect?

Options

  1. AIn the -helix structure, the polypeptide chain is stabilized by intermolecular hydrogen bonding.
  2. BIn the -pleated sheet structure, adjacent polypeptide chains are held together by intermolecular hydrogen bond
  3. CThe secondary structure of a protein arises due to the regular folding of the backbone of the polypeptide chai
  4. DThe primary structure of a protein refers to the specific sequence in which amino acids are linked together.

Correct answer

A. In the -helix structure, the polypeptide chain is stabilized by intermolecular hydrogen bonding.

Step-by-step solution

Let us evaluate each statement: Statement 1 is incorrect. In the -helix structure, the polypeptide chain twists into a right-handed screw, and the structure is stabilized by intramolecular hydrogen bonding between the - C=O of one amino acid residue and the - NH - group of the fourth amino acid residue along the same chain. Statement 2 is correct. In the -pleated sheet structure, all peptide chains are stretched out to nearly maximum extension and then laid side by side, held together by intermolecular hydrogen bon

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