When a globular protein undergoes denaturation, which of the following chemical bonds or interactions remains unaffected?

Step-by-step solution

During the denaturation of proteins, the secondary and tertiary structures are destroyed. This involves the disruption of weak interactions that stabilize these higher-order structures, such as hydrogen bonds, hydrophobic interactions, and ionic bonds. However, the primary structure of the protein remains intact. The primary structure is the sequence of amino acids linked together by strong covalent peptide bonds. Therefore, peptide bonds are not broken during denaturation. Answer: Peptide bonds