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MHT CET Medical202621 April 2026Morning ShiftBiologyMolecular Basis of InheritanceActual

The enzyme that facilitates local unwinding of DNA duplex during transcription is-------------------.

Options

  1. ADNA helicase
  2. BDNA polymerase
  3. CRNA polymerase
  4. DDNA ligase

Correct answer

C. RNA polymerase

Step-by-step solution

During transcription, RNA polymerase binds to the promoter region of the DNA and initiates the process. It not only catalyzes the polymerization of RNA but also facilitates the local unwinding (opening) of the DNA double helix to form the transcription bubble, allowing the template strand to be read. DNA helicase is responsible for unwinding DNA during replication, not transcription. DNA polymerase synthesizes DNA during replication, and DNA ligase joins DNA fragments. Answer: RNA polymerase

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