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NEET2008ChemistryHydrocarbonsActual

The relative reactivities of acyl compounds towards nucleophilic substitution are in the order of

Options

  1. AAcyl chloride > Ester > Acid anhydride > Amide
  2. BAcyl chloride > Acid anhydride > Ester > Amide
  3. CEster > Acyl chloride > Amide > Acid anhydride
  4. DAcid anhydride > Amide > Ester > Acyl chloride

Correct answer

B. Acyl chloride > Acid anhydride > Ester > Amide

Step-by-step solution

Better is the leaving group higher will be the reactivity of acyl compounds towards nucleophilic acyl substitution. Weaker is the base, better is the leaving group. Weaker bases are derived from stronger acids.

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