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NEET 2021
Exam
NEET
Year
2021
Subject
Zoology
Chapter
Biotechnology and Its Applications

NEET 2021 · Zoology · Biotechnology and Its Applications

With regard to insulin choose correct options. (a) C-peptide is not...

With regard to insulin choose correct options.

(a) C-peptide is not present in mature insulin.

(b) The insulin produced by rDNA technology has C-peptide.

(c) The pro-insulin has C-peptide.

(d) A-peptide and B-peptide of insulin are interconnected by disulphide bridges.

Options

  1. A(b) and (d) only
  2. B(b) and (c) only
  3. C(a), (c) and (d) only
  4. D(a) and (d) only

Correct answer

C. (a), (c) and (d) only

Step-by-step solution

Insulin is a protein hormone that is composed of two chains, an A-chain having 2121 amino acids and a B-chain having 3030 amino acids, linked together by disulphide bonds (S-S). Insulin is derived from a 74−74 -amino acid prohormone molecule called proinsulin having C-peptide and this is removed before the processing of mature insulin and during the production of recombinant insulin, the two chains were separately produced and then linked with each other. C-peptide is absent in mature insulin.

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