NEET2022ZoologyBiotechnology and Its ApplicationsActual
Statements related to human Insulin are given below: Which statement(s) is/are correct about genetically engineered Insulin? (a) Pro-hormone insulin contain extra stretch of C-peptide. (b) A-peptide and B-peptide chains of insulin were produced separately in E. coli , extracted and combined by creating disulphide bond between them. (c) Insulin used for treating Diabetes was extracted from cattle and pigs. (d) Pro-hor
Options
- A(b) only
- B(c) and (d) only
- C(c), (d) and (e) only
- D(a), (b) and (d) only
Correct answer
A. (b) only
Step-by-step solution
In the year 1983, the American company Eli Lilly prepared two DNA sequences corresponding to A and B, chains of human insulin and introduced them in plasmids of E. coli to produce insulin chains. Chains A and B were produced separately, extracted and combined by creating disulfide bonds to form human insulin.