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NEET 2020
Exam
NEET
Year
2020
Subject
Zoology
Chapter
Molecular Basis of Inheritance

NEET 2020 · Zoology · Molecular Basis of Inheritance

Which of the following statements is correct?

Which of the following statements is correct?

Options

  1. AAdenine pairs with thymine through one H-bond
  2. BAdenine pairs with thymine through three H-bonds
  3. CAdenine does not pair with thymine
  4. DAdenine pairs with thymine through two H-bonds

Correct answer

D. Adenine pairs with thymine through two H-bonds

Step-by-step solution

Erwin Chargaff’s rules: Chargaff’s along with his colleagues, performed base composition studies and put forward certain generalizations for double-stranded DNA, called Chargaff’s rule (Not applicable for single-stranded DNA).
i) Purines and pyrimidines occur in equal amounts.
ii) Purines found in DNA are adenine and guanine. Pyrimidines of DNA are thymine and cytosine.
A + G = T + C
iii)A+GT+C=1\dfrac{A + G}{T + C} = 1 this value is constant for all species.
iv) Base ratio A+TG+C\dfrac{A + T}{G + C} is specific for a species. It is used to identify the species. It is less than one in prokaryotes, e.g., E. coli = 0.92, and more than one in eukaryotes, e.g., Human = 1.52.
v) Sugar deoxyribose and phosphate residues occur in equal number.
vi) Purine adenine is equimolar with pyrimidine thymine
vii) Purine guanine is equimolar with pyrimidine cytosine.
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