NEETZoologyBiotechnology - Principles and Processes
What is a plasmid?
Options
- AA type of bacterium
- BA viral particle
- CA piece of cut DNA
- DAutonomously replicating circular extra-chromosomal DNA
Correct answer
D. Autonomously replicating circular extra-chromosomal DNA
Step-by-step solution
The construction of the first recombinant DNA emerged from the possibility of linking a gene encoding antibiotic resistance with a native plasmid (autonomously replicating circular extra-chromosomal DNA) of Salmonella typhimurium. Stanley Cohen and Herbert Boyer accomplished this in 1972 by isolating the antibiotic resistance gene by cutting out a piece of DNA from a plasmid which was responsible for conferring antibiotic resistance