Quantrex Quantrex AcademyJEE · NEET · NDA PYQs with solutions Open app
AIIMS 2003
Exam
AIIMS
Year
2003
Subject
Chemistry
Chapter
Coordination Compounds

AIIMS 2003 · Chemistry · Coordination Compounds

The complex used as an anti-cancer agent is

The complex used as an anti-cancer agent is

Options

  1. Amer- $\left[\mathrm{Co}\left(\mathrm{NH}_3\right)_3 \mathrm{Cl}_3\right]
  2. Bcis-[ \left.\mathrm{PtCl}_2\left(\mathrm{NH}_3\right)_2\right]
  3. Ccis- $\mathrm{K}_2\left[\mathrm{PtCl}_2 \mathrm{Br}_2\right]
  4. DNa2[CoCl4]\mathrm{Na}_2\left[\mathrm{CoCl}_4\right].

Correct answer

B. cis-[ \left.\mathrm{PtCl}_2\left(\mathrm{NH}_3\right)_2\right]

Step-by-step solution

Cis-[ \left[\mathrm{PtCl}_2\left(\mathrm{NH}_3\right)_2\right]isusedasananti−canceragent,calledascisplatinandishighlytoxic.Oninjecting,themorereactiveis used as an anti-cancer agent, called as cisplatin and is highly toxic. On injecting, the more reactive\mathrm{Cl}groupsarelostsothePtatombondstoagroups are lost so the Pt atom bonds to a\mathrm{N} atom in guanosine (part of the DNA molecule). Those cells which are undergoing cell division are attacked by cisplatin.
Practice Coordination Compounds on Quantrex Academy →

More from Coordination Compounds

[Ti(H_2O)_6]^ 2+ is a colored compound where as [Zn(H_2O)_6]^ 2+ is colorless, because MHT CET Medical 2026What is coordination number of central metal ion in cisplatin ? MHT CET Medical 2026Which of the following complexes exhibits solvate isomerism? MHT CET Medical 2026What type of ligand the ethylenediamine is? MHT CET Medical 2026Which of the following isomers is used in the treatment of cancer? MHT CET Medical 2026Identify the geometry and magnetic behavior of the complex [Ni(CO)_4] . MHT CET Medical 2026Identify the correct match from the following for coordinate complex (column A) and… MHT CET Medical 2026Which type of complex is Diamminedichloroplatinum(II)? MHT CET Medical 2026 Full Coordination Compounds list All AIIMS PYQs