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NTA Abhyas JEE Main2020ChemistryCarboxylic Acid DerivativesPractice

Which of the following functional groups is generally least reactive towards nucleophilic substitution reactions?

Options

  1. AAmide
  2. BEster
  3. Cacid chloride
  4. DAcid Anhydride

Correct answer

A. Amide

Step-by-step solution

Reactivity order R - c O | | - Cl > R - c O | | - o - c O | | - R > R - c O | | - OR > R - c O | | - NH 2 Reactivity for nucleophilic in decreasing order.

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