NTA Abhyas JEE Main2020ChemistryAminesPractice
Gabriel phthalimide synthesis can be used for the preparation of amine from
Options
- AC H 3 C H 2 B r
- BC H 3 3 C B r
- Cp - C H 3 O C 6 H 4 B r
- Dp - C H 3 C 6 H 4 B r
Correct answer
A. C H 3 C H 2 B r
Step-by-step solution
C H 3 C H 2 B r is more reactive in S N 2 reactions. In ( C H 3 ) 3 C B r , steric hindrance at the carbon of C - B r is very high, therefore, the nucleophilic attack of phthalimide anion is mechanically hindered. The - C H 3 and - O C H 3 are electron-donating groups, which do not activate Br atom for nucleophilic substitutions reactions. Hence, compounds C and D are not also used for the preparation of amines.